Clinical EvidenceBehind EXG™
Research-backed cardiac monitoring technology addressing systemic challenges in ECG performance and STEMI detection accuracy.
This is a Big
Costly Problem
Global population living with heart and circulatory diseases
Source: British Heart Foundation 2023
30% of Americans defined as clinically obese
Source: CDC 2022
Global deaths attributable to heart and circulatory diseases
Source: British Heart Foundation 2023
Annual heart attack wrongful death exposure (1.5% misdiagnosis rate, 40% malpractice win rate, $400k avg. indemnity payment)
Source: Newman et al. 2022
Annual U.S. missed/delayed MI detection rate
Source: Newman et al. 2022
Current AI Algorithms Face a Fundamental Challenge
Current AI algorithms have utilized a trove of ECG data collected over many years, most of which were done wrong. The foundation of modern cardiac diagnostics is built on systematically flawed data, leading to continued misdiagnosis and delayed treatment.
Macro-Market Fundamentals
Driving Demand
Global population living with heart and circulatory diseases
Source: British Heart Foundation 2023
30% of Americans defined as clinically obese
Source: CDC 2022
Global deaths attributable to heart and circulatory diseases
Source: British Heart Foundation 2023
Annual heart attack wrongful death exposure (1.5% misdiagnosis rate, 40% malpractice win rate, $400k avg. indemnity payment)
Source: Newman et al. 2022
Annual U.S. missed/delayed MI detection rate
Source: Newman et al. 2022
Current ECG Systemic Problems & Errors
Challenges with Current Standard-of-Care
Electrode Misplacement Crisis
- 2 cm misplacement can hide a heart attack (false negatives)
- 72% of unnecessary Cath Lab activations linked to ECG misinterpretation (false positives)
Critical Time Delays
- Each 1 min delay increases mortality 2%
- 29% of suspected STEMI patients did not receive ECG within 10 minutes
Unreliable Transport Monitoring
- Unreliable signal during transport
- Poor tolerance to motion
- 28% transmission rates during acute MI
- Serial ECGs significantly enhance STEMI detection but are rarely performed
CPR & Adhesion Failures
- Incompatible during CPR
- Poor adhesion in critical situations
- Cannot maintain continuous monitoring during resuscitation
EXG™
Addressing every systemic challenge in current ECG standard-of-care
AHA-compliant electrode placement eliminates user error
Rapid <60s deployment reduces critical time delays
Continuous 12-18 lead monitoring maintains signal quality during transport
Radiolucent design allows monitoring during all procedures including CPR
Superior adhesion maintains connection in high-motion environments and CPR
Real-time monitoring enables serial ECG analysis for enhanced STEMI detection
Built on Accurate Data, Designed for Real-World Performance
The EXG™ platform solves the foundational data quality problem while addressing every practical challenge faced by emergency medicine professionals in the field.
Explore EXG™ PlatformClinical Citations
Peer-reviewed research supporting the need for improved ECG technology
Anderson, H. V., et al.
2022 ACC/AHA Key Data Elements and Definitions for Chest Pain and Acute Myocardial Infarction
Journal of the American College of Cardiology (2022) vol. 80, no. 17, pp. 1660–1700
View SourceHsia, Renee Y., et al.
A US National Study of the Association Between Income and Ambulance Response Time in Cardiac Arrest
JAMA Network Open (2018) vol. 1, no. 7, e185202
View SourceMcClung, Christian D., et al.
Emergency Provider Performance of 12-Lead Electrocardiography
American Heart Association Resuscitation Science (2023)
View SourceGE HealthCare
Avoiding STEMI and NSTEMI Misdiagnoses with Fast, Accurate ECG Interpretation
European Heart Journal: Acute Cardiovascular Care (summarized by GE HealthCare) (2023)
View SourceBond, R. R., et al.
The Effects of Electrode Misplacement on Clinicians' Interpretation of the Standard 12-Lead Electrocardiogram
European Journal of Internal Medicine (2012) vol. 23, no. 7, pp. 610–615
View SourceBosson, Nichole, et al.
The Utility of Prehospital ECG Transmission in a Large EMS System
Prehospital Emergency Care (2015) vol. 19, no. 4, pp. 496–503
View SourceAboal, Jaime, et al.
Time from Electrocardiographic Diagnosis of ST-Elevation Myocardial Infarction to Guidewire Crossing
Emergencias (2021) vol. 33, pp. 195–202
View SourceLange, David C., et al.
Cancellation of the Cardiac Catheterization Lab After Activation for ST-Segment-Elevation Myocardial Infarction
Circulation: Cardiovascular Quality and Outcomes (2018) vol. 11, e004464
View SourceCui, Eric R., et al.
Disparities in Emergency Medical Services Time Intervals for Patients with Suspected Acute Coronary Syndrome: Findings from the North Carolina Prehospital Medical Information System
Journal of the American Heart Association (2021) vol. 10, no. 15, e019305
View SourceBorquez, E. A., et al.
Evaluating Predictors of Door-to-EKG Times
Annals of Emergency Medicine (2012) abstract
View SourceHenry, Timothy D., et al.
Economic Impact of False ST-Segment Elevation Myocardial Infarction Cardiac Catheterization Laboratory Activations at a Major Los Angeles County STEMI-Receiving Center
Journal of the American College of Cardiology (2016) vol. 67, no. 13
View SourceHarrigan, Richard A., et al.
Electrocardiographic Electrode Misplacement, Misconnection, and Artifact
The Journal of Emergency Medicine (2012) vol. 43, no. 6, pp. 1038-1044
View SourceO'Connor, Robert E., et al.
Emergency Medical Services Management of ST-Segment Elevation Myocardial Infarction in the United States—A Report from the American Heart Association Mission: Lifeline Program
American Journal of Emergency Medicine (2014) vol. 32, no. 8, pp. 856-863
View SourceCui, Eric R., et al.
Emergency Medical Services Time Intervals for Acute Chest Pain in the United States, 2015–2016
Prehospital Emergency Care (2020) vol. 24, no. 4, pp. 557–565
View SourceDegheim, George, et al.
False Activation of the Cardiac Catheterization Laboratory: The Price to Pay for Shorter Treatment Delay
JRSM Cardiovascular Disease (2019) vol. 8, pp. 1–5
View SourceFaour, A., et al.
Utility of Prehospital Electrocardiogram Interpretation in ST-Segment Elevation Myocardial Infarction Utilizing Computer Interpretation and Transmission for Interventional Cardiologist Consultation
Journal of Electrocardiology (2019) vol. 55, pp. 8–13
View SourceMcClung, Christian D., et al.
FMC-to-ECG Interpretation <10 Minutes: A Value Stream Analysis
Unpublished workflow analysis (2023)
Farrell, R. M., et al.
Effects of Limb Electrode Placement on the 12- and 16-Lead Electrocardiogram
Journal of Electrocardiology (2008) vol. 41, no. 2, pp. 124-130
View SourceMuhrbeck, Josephine, et al.
Few with ST-Segment Elevation Myocardial Infarction Are Diagnosed within 10 Minutes from First Medical Contact, and Women Have Longer Delay Times than Men
IJC Heart & Vasculature (2020) vol. 26, 100458
View SourceDrew, Barbara J., et al.
Frequency, Characteristics, and Clinical Significance of Transient ST Segment Elevation in Patients with Acute Coronary Syndromes
European Heart Journal (2002) vol. 23, no. 12, pp. 941–947
View SourceGrennan, Matthew, et al.
Hospital Management Practices and Medical Device Costs
Health Services Research (2022) vol. 57, no. 2, pp. 227–236
View SourceHillinger, Petra, et al.
Prospective Validation of Current Quantitative Electrocardiographic Criteria for ST Elevation Myocardial Infarction
International Journal of Cardiology (2019) vol. 292, pp. 1–12
View SourceHoekstra, James W., et al.
Acute Detection of ST-Elevation Myocardial Infarction Missed on Standard 12-Lead ECG With a Novel 80-Lead Real-Time Digital Body Surface Map
Annals of Emergency Medicine (2009) vol. 54, no. 6, pp. 779–788
View SourceHolmes, James F., et al.
Time Required for Electrocardiogram Interpretation in the Emergency Department
Academic Emergency Medicine (2022) vol. 29, no. 5, pp. 662–664
View SourceHadjianton, Antonia, et al.
Electrode Misplacement in Electrocardiography: A Systematic Review
Journal of Electrocardiology (2020)
View SourceWinters, Leigha J., et al.
Time Required for Electrocardiogram Interpretation in the Emergency Department
Academic Emergency Medicine (2022)
View SourceGE HealthCare
How Accurate ECG Interpretation Can Mitigate Healthcare Costs
GE HealthCare Insights (2024)
View SourceHansen, Steen, et al.
Importance of Hospital Entry: Walk-In STEMI and Primary Percutaneous Coronary Intervention
European Heart Journal: Acute Cardiovascular Care (2015) vol. 4, no. 6, pp. 545–552
View SourceYoon, Sunyoung, et al.
Twelve-Lead Electrocardiogram Acquisition With a Patchy-Type Wireless Device in Ambulance Transport
JMIR mHealth and uHealth (2021) vol. 9, no. 4, e24142
View SourceKragholm, Kristian, et al.
Improvement in Care and Outcomes for Emergency Medical Service-Transported Patients With ST-Segment-Elevation Myocardial Infarction
Circulation (2017) vol. 135, no. 5, pp. 456-468
View SourceLange, David C., et al.
Cancellation of the Cardiac Catheterization Laboratory After Activation for ST-Segment Elevation Myocardial Infarction
Circulation: Cardiovascular Quality and Outcomes (2018) vol. 11, no. 8, e004464
View SourceLee, Thomas H., et al.
Clinical Characteristics and Natural History of Patients With Acute Myocardial Infarction Sent Home From the Emergency Room
The American Journal of Cardiology (1987) vol. 60, no. 3, pp. 219-224
View SourceMcCarthy, Bruce D., et al.
Missed Diagnoses of Acute Myocardial Infarction in the Emergency Department
Annals of Emergency Medicine (1993) vol. 22, no. 3, pp. 579–582
View SourceMiedema, Michael D., et al.
Causes of Delay and Associated Mortality in Patients Transferred With ST Segment-Elevation Myocardial Infarction
Circulation (2011) vol. 124, no. 15, pp. 1636–1644
View SourceDauerman, Harold L., et al.
Nationwide Analysis of Patients With ST-Segment-Elevation Myocardial Infarction Transferred for Primary Percutaneous Intervention
Circulation: Cardiovascular Interventions (2015) vol. 8, no. 6, e002450
View SourceBaskett, Peter J. F.
Frank Pantridge and the World's First Miniature Portable Defibrillator
Resuscitation (2005) vol. 65, no. 1, p. 5
View SourcePope, J. Hector, et al.
Missed Diagnoses of Acute Cardiac Ischemia in the Emergency Department
The New England Journal of Medicine (2000) vol. 342, no. 16, pp. 1163–1170
View SourceStopyra, Jason P., et al.
Prehospital Time Disparities for Rural Patients with Suspected STEMI
Prehospital Emergency Care (2023) vol. 27, no. 4, pp. 488–495
View SourceOwnbey, Micah, et al.
Prevalence and Interventional Outcomes of Patients with Resolution of ST-Segment Elevation between Prehospital and In-hospital ECG
Prehospital Emergency Care (2014) vol. 18, no. 2, pp. 174–179
View SourceNewman-Toker, David E., et al.
Rate of Diagnostic Errors and Serious Misdiagnosis-Related Harms for Major Vascular Events, Infections, and Cancers
Diagnosis (2020) vol. 7, no. 3, pp. 225-240
View SourceRouan, Gregory W., et al.
Clinical Characteristics and Outcome of Acute Myocardial Infarction in Patients with Initially Normal or Nonspecific Electrocardiograms
The American Journal of Cardiology (1989) vol. 64, no. 18, pp. 1087-1092
View SourceSchull, Michael J., et al.
The Risk of Missed Diagnosis of Acute Myocardial Infarction Associated with Emergency Department Volume
Annals of Emergency Medicine (2006) vol. 48, no. 6, pp. 647-655
View SourceReview Our Clinical Evidence
Request detailed clinical data and research supporting the EXG™ platform